NetSpot
Neuroendocrine Tumor
Neuroendocrine tumors tend to be quite small and are relatively uncommon, but with increasing incidence and prevalence. They can occur anywhere in the body, from intestines to the lungs to the stomach and pancreas.
NetSpot is a PET/CT agent that binds to somatostatin receptors, which are overt-expressed in NETs. By attaching to these tumor cells, NetSpot enables highly accurate, three-dimensional imaging that can improve tumor detection and disease evaluation.
Approved by the FDA in 2016, NetSpot is a new tool which has revolutionized the standard positron emission tomography (PET). PET scans on their own tend not to be effective in detecting these types of tumors, due to their slower uptake of glucose (unlike other cancer tumors).
But now, NetSpot has been developed. Previously, PET scans relied on tracers which identified tumors using radiolabeled glucose. NetSpot can identify even the smallest abnormalities with more success than other type of imaging agent currently in use.
The NetSpot edge
NetSpot offers significant improvements for patients and health care providers compared with previous scanning methods.
NETs absorb glucose very slowly in comparison to other cancers but contain somatostatin receptors.
With NetSpot, tumor detection is enhanced is 3 key ways:
Faster
This study provides a faster process, improved imaging for earlier detection, helps determine the best treatment options, and allows for better monitoring of recurrence.
Higher quality images
The images produced by the PET scan used in combination with NetSpot are of a much higher resolution, which makes abnormalities easier to spot – even miniscule ones.
Guides therapeutic response
NetSpot takes only 2 hours, whereas the octreoscan traditionally used as a diagnostic is a three-day process.
How to prepare
Before your NetSpot PET scan, you’ll need to advise your doctor of any and all medications, whether over the counter, prescription, herbal supplements or vitamins. If you’re taking Somatostatin analogs, it’s important that your doctor know. If you are taking short-acting versions of this medication you can use them up to 24 hours prior to your procedure.
Hydrate well before your scan.
What to expect
Once you’re injected with NetSpot, your technician will ask that you wait between 40 and 90 minutes to proceed with the scan. Once the scan is started, the procedure will take 30 – 60 minutes.
You’ll be asked to lie as still as possible during the scan. Movement can impact the quality of captured images.
Results will be sent to your doctor.